Implementing quantitative and objective diagnostic biomarkers is a critical element in clinical trial protocol design and execution. EyeKor and its partners has deep expertise to assist you choosing the right biomarkers that reflect accurately the characteristics of disease progression and treatment effects.

 

Dry Age-Related Macular Degeneration (AMD)

  • Retinal thickness and volume assessment on the central retina from SD-OCT

  • Classification of retinal drusen and pigment changes according to the AREDS Severity Scale

  • Measurement of area, perimeter, and proximity to fovea of geographic atrophy lesion from autofluorescence images

  • Measurement of area of geographic atrophy from SD-OCT

  • Interpretation and measurement from SD-OCT of outer retina morphology

 

Neovascular AMD

  • Retinal thickness and volume assessment on the central retina from SD-OCT

  • Classification and measurement of area of neovascular lesion components from fluorescein angiography

  • Evaluation of polypoidal choroidopathy from indocyanine green angiography (ICG)

  • Evaluation and measurement of neovascular lesion components from SD-OCT

 

Diabetic Retinopathy

  • Retinal thickness and volume assessment on the central retina from SD-OCT

  • Classification of diabetic retinopathy severity according to the ETDRS Severity scale from color photographs

 

Diabetic Macular Edema (DME)

  • Evaluation of macular edema from fluorescein angiograms for leakage and nonperfusion

  • Assessment and measurement of DME from SDOCT images for morphology and retina and retinal layer volumes

 

Retina Vascular Occlusion

  • Evaluation of macular edema from fluorescein angiograms for leakage and nonperfusion

  • Retinal thickness and volume assessment on the central retina from SD-OCT

  • Assessment and measurement of macular edema from SD-OCT images for morphology and retina and retinal layer volumes

 

Uveitis

  • Evaluation of macular edema from fluorescein angiograms for leakage and nonperfusion

  • Retinal thickness and volume assessment on the central retina from SD-OCT

  • Assessment and measurement of macular edema from SDOCT images for morphology and retina and retinal layer volumes

  • Scoring of vitreous haze

 

Cataract

  • Opacity scoring according to the AREDS Lens Scale from red reflex and slit lamp photographs

 

Cornea Endothelial Cell

  • Endothelial cell density and morphometry from specular microscopy